Clinical Studies Search

Protocol Summary


Protocol No.
PSCI-25-034
Prinicipal Investigator
Komiya, Takefumi
Phase
Phase III
Age Group
Adult
Scope
National
Secondary Protocol No.
D763QC00001
Title
A Phase III, Randomised, Open-Label, Multicentre Study of Datopotamab Deruxtecan or Docetaxel in Previously Treated TROP2-positive Advanced or Metastatic Non-squamous Non-Small Cell Lung Cancer Without Actionable Genomic Alterations (TROPION-Lung17)
Objective
1. To assess the superiority of Dato-DXd vs docetaxel by assessment of PFS by BICR in participants with TROP2 QCS-NMR positive non-squamous NSCLC without AGA

2. To assess the superiority of Dato-DXd vs docetaxel by assessment of OS in participants with TROP2 QCS-NMR positive non-squamous NSCLC without AGA
Applicable Disease Sites
Lung
Status
Open
Participating Institutions
Hershey Medical Center