Clinical Studies Search

Protocol Summary


Protocol No.
PSCI-21-188
Prinicipal Investigator
Aregawi, Dawit
Phase
Phase II
Age Group
Adult
Scope
National
Secondary Protocol No.
ONO-4059-09
Title
An open-label phase II study to investigate the efficacy, safety, and pharmacokinetics of tirabrutinib in patients with Primary Central Nervous System Lymphoma (PCNSL)
Objective
To evaluate the efficacy of tirabrutinib monotherapy in patients with R/R PCNSL.
To evaluate the safety of tirabrutinib monotherapy in patients with R/R PCNSL.
To evaluate the PK of tirabrutinib monotherapy in patients with R/R PCNSL.
Applicable Disease Sites
Brain and Nervous System
Status
Open
Participating Institutions
Hershey Medical Center