Cancer biobank for developing novel diagnostic biomarkers and therapeutic targets
Objective
The purpose of this study is to identify novel blood-based biomarkers and targets for early detection and treatment of cancer in collaboration with Ilias Georgakopoulos-Soares, Ph.D. (Co-Investigator).
The aim of this study is to generate a biobank consisting of blood and tumor specimens along with the clinical, pathological, and molecular data in patients with cancer. The plasma-derived cell-free (cf) DNA, RNA, and other molecules will be analyzed in Ilias Georgakopoulos-Soares, Ph.D. s research laboratory to identify cancer-specific mutations.
This study is designed to test the hypothesis that mutational signatures of circulating cfDNA, cfRNA, and other molecules can be developed as diagnostic biomarkers for screening and early detection of cancer, and as targets for anti-cancer therapies.